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3-Azaspiro[5.5]undecane hydrochloride

CAS: 1125-01-5 F: C10H20ClN W: 189.73

3-Azaspiroundecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A
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Bioactivity 3-Azaspiro[5.5]undecane (4,4-Pentamethylenepiperidine) hydrochloride is an inhibitor targeting the WT influenza A virus M2 (A/M2), with an IC50 of 1 μM[1].
Target IC50: 1 μM (influenza A virus M2)
Name 3-Azaspiro[5.5]undecane hydrochloride
CAS 1125-01-5
Formula C10H20ClN
Molar Mass 189.73
Appearance 固体
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Wang J, et al. Exploring the Requirements for the Hydrophobic Scaffold and Polar Amine in inhibitors of M2 from Influenza A Virus. ACS Med Chem Lett. 2011 Apr 14;2(4):307-312.